Wednesday, 23 October 2013

US Attributes of Thyroid Malignancy: Pearls and Pitfalls

http://papillarythyroidcancer.blinkweb.com/
US Attributes of Thyroid Malignancy: Pearls and Pitfalls
Introduction

Thyroid nodules are extremely common and could be viewed at ultrasonography (US) in 50% from the adult population. Thyroid malignancy is comparatively rare and it is diagnosed in approximately 25,000 patients each year in the usa (1). The most typical reason for benign thyroid nodules is nodular hyperplasia (2). Although under 7% of thyroid nodules are malignant (2), it is important they be accurately identified. The imaging modality preferred by your research of thyroid nodules is high-resolution US. US is often misperceived as unhelpful in distinguishing between benign and malignant thyroid nodules. Although individual US features might be of limited value, when multiple indications of thyroid malignancy come in combination you'll be able to make a precise prediction. The nodule then might be further assessed with fine-needle aspiration (FNA).

Scintigraphy sits dormant routinely to evaluate thyroid nodules. It's primarily useful in patients having a suppressed thyroid-stimulating hormone level, in whom it enables assessment from the functional activity of the thyroid nodule as well as the entire gland. A functioning, or “hot,” thyroid nodule isn't malignant, with simply several reported installments of such malignancy (3-10). Although a nonfunctioning, or “cold,” nodule at scintigraphy is often considered to indicate a heightened chance of thyroid malignancy, as much as 77% of cold thyroid nodules might be benign (4,11). Thyroid scintigraphy therefore is unhelpful for differentiating a benign nodule from the malignant one, and it is utility for that routine evaluation of thyroid nodules is restricted.

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